MPXV (Monkeypox virus) is a viral illness caused by the monkeypox virus, a member of the Orthopoxvirus genus. There are two distinct clades of the virus: Clade I with sub-clades Ia and Ib, and clade II, with subclades IIa and IIb.

Transmission occurs through direct contact with an infected individual, contaminated materials, or infected animals. The virus can enter the body through broken skin, the respiratory tract, or mucous membranes.

Common symptoms of mpox include a skin rash or mucosal lesions, which can persist for 2–4 weeks, often accompanied by fever, headache, muscle aches, back pain, fatigue, and swollen lymph nodes. These symptoms typically appear within a week, but can manifest anywhere between 1 to 21 days after exposure. While the symptoms generally last 2–4 weeks, they may persist longer in individuals with weakened immune systems.

VIASURE Monkeypox Virus Real Time PCR Detection Kit is a real-time PCR test designed for the qualitative identification of DNA from Monkeypox virus in lesion swabs from individuals suspected of Monkeypox virus infection by their healthcare professional (HCP).

Infection due to Monkeypox Virus displays similar symptoms and has a similar transmission route as other pathogens such as Varicella Zoster Virus, Herpes Virus 1, Herpes Virus 2, Treponema pallidum or C. trachomatis making clinical diagnosis difficult.