H.PYLORI + TRANSFERRIN

Helicobacter pylori (H. pylori) is a spiral-shaped bacterium that is found in the gastric mucous layer or adherent to the epithelial lining of the stomach. H. pylori causes more than 90% of duodenal ulcers and up to 80% of gastric ulcers.

The importance of Helicobacter pylori testing has increased due to the strong correlation between the presence of bacteria and confirmed gastrointestinal diseases (stomach and duodenum) like gastritis, peptic ulcer disease and gastric carcinoma.

Patients suffering from gastro-duodenal ulcer may develop complications such as upper gastrointestinal bleeding or perforation.

A precise diagnosis of H. pylori after eradication reduces significantly the risk of ulcer reactivation, and thus prevents new episodes of upper gastrointestinal bleeding.

Transferrin is a blood-derived component. In gastrointestinal bleeding diseases, it may be leaked into gastrointestinal tract and then discharged with the feces.

Transferrin is stable in feces and a good marker to detect gastrointestinal bleeding. This immunochromatographic assay detects simultaneously H. pylori and human transferrin in stool samples, obtaining more accurate testing results regarding the H. pylori infection.

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